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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2346fc5bca554488557a9033599d3d7bafd056de9694b25a6eabf8946f45e140' 
  AND token = 'U4x9M2nQvom6a/zuxrEBOmDQpAH2pI/rfWWMxu1yjVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}