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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c54b40ea822a1f340d65e9cc659573ac1b7a18c66214aad8032032b81b06d40' 
  AND token = 'sTx8BfmD9tn+p0dmQiAJo0XMQIgnVAdtp7c1wV4vlo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}