SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f50452ac1d2fc2a631f98fee8ec9881600735ed8e7b37b54a30318e54ae8fef' 
  AND token = 'HcD1kU5hk/gLl4Qz0HXR7JsE+uKtQ5tGHUvCWSQX/q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}