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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b359e3a7a6ab9eb8afa2a9f6eb3dcfe740e408da53a5afdc3a0eceff8ebb50a2' 
  AND token = 'RiZcS5cJO5i5UWydY/5vv9I3SYgoR+8idlDw8BGYZh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}