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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b92c2be890ef7b133a2140478d8130bd3355137be93595001180877f33d20b90' 
  AND token = 'MdSA6mW/KuJbZ/LR44tr1Aub8N9ravzeur1dp0qEZ0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}