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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2646f75fe71dc39cc4318e4335022b35728ca437e20400322b309678a8c7e1b6' 
  AND token = 'Z1QTKgmfkpdvcyrMxMsRh8eHWgZcaqvG3rS6qZ0FzpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}