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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b6b692410a660da5e262028a8b13ba447e48519a57b75a3788547579b02870' 
  AND token = 'EUziNRkzlQU46aCGRbSVv9VR+E/3Wh+dZtpS7c3h+08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}