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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b780aefdf871b264e5240ca88234d8f946e06ee9e50e98f1c41873f89865be7' 
  AND token = 'CK94eK3uhxEa+YJ1h+kvVoito+uAIEV1h6bKKCoNHBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}