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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed5b92ef449601c944b7b4c92cf94e8b66e14e50aeae3a27585040af6e0341b' 
  AND token = '+fLZTcKduCCadjSPcwyrogvuKLWIQkrq7EbBCzlHgB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}