SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52685fe47a73277190213b16e474feddf23f2707ae14cfc7aee4932aec1953d5' 
  AND token = 'CITc+S0DpWdYT5W+wM+2bkUBDuHwMVmmrPgK9cgJGfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}