SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a691e6d0c5b7018347cd52fd752e49b237b715e292cf413f857d6dd5026527' 
  AND token = 'CnZCvGVhsUs2S7hWqiftq3/QiSaY2TC6yhohgfAlwQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}