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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ac8ea6419d917db46db971ee67cee4c4dc6014546e5216228f6f2661fb1099' 
  AND token = 'AlsTvYY/7VhKJi5OhoceYvul4gCTFUSCS/+f3FvM6hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}