SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a281ad08016a96ef2fdb580a2608e92ce7aea636c2bd1db8d0ca1364b478f1' 
  AND token = 'hA1eLYapY0BPnBPbygjtXr+6BFq0uxE5Zo14JAUZl9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}