SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91121f27f82bf2e40f68e2378e6c16a7ac54c1c49e6183d792bf73df440a033a' 
  AND token = 'a7bFbR2fLFMTDCRccm9i10Qe3bzN+szCd8s22NUAV94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}