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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e575d098aa1553251f9c41e4c1afbf3ef8333e46400a96c042417b00cb5c6c' 
  AND token = 'XZ45GgbstdnWswNqsZ288IHXTq0xsllvtWiQ3ipzJAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}