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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab18734144b01096b02e18263d2c05a5bad7d6cab440b57f51152146b12e890' 
  AND token = '4ZZy7rsuEmbAj/znSebozNsls/OjdeETk1ruqJ4KeSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}