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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64333725c820cacbf764b7a2ee8c44343ac9d1d9fca236f96e46e92396bbe90c' 
  AND token = 'jaSq4TeDB8PAmntdIT+j7eojYa0djmqNJzOJi3Wiz4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}