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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f67a34e4290f6cfb4b979b27dafbbfc8067dda7966f91f1a66dda3c1fea232f' 
  AND token = 'gGhjCOf/Oq1uEI+L8GxsissF/Ihq2kn46EppRNotVfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}