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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ceddf22a3cd687d81b5cce4e272b49e92eef58d5d262a2a067141808297562b' 
  AND token = 'aBe3y48nm/w8OD860WlKFTn1+4melAor77XBhjgUEGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}