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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0d8b91418f65d2ea4e06b5f785252ba1decbf366ca811c3f5dc30e1f3424b04' 
  AND token = 'pzDQKXaIvpkI5QyX9bsrgNb1b4yWKS+MjYYjgXbYcg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}