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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cad5241d3d95cf1dee56750a1f698d9643f4b2fe96869cae97d8dcf7c16f4fcc' 
  AND token = 'EIJMPI7yX7E4hAMxNwaTEQgC9G6wzg9VfDDZGy0mE4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}