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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '338b713e070932e35558f0a757dba72d857c6037850a2583de52c5b42dc4c402' 
  AND token = 'GC118OY9PKr3N34OQoqA644QQA8b86II9eZT+wS27KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}