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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0180b8fff9e389ab22acdd06b052ea0e2687f52cc7d1a9c3118b8914aeb4e69' 
  AND token = 'HtS0CoR10cCbwb+gmf/B3GZFw5gIrs49eNBqZfb21DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}