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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b07462a396c5ce27f800fdc90ce7b09e420a5eea5a057018dd62c367196950' 
  AND token = 'vkSXXcYiRdZj+U+Tt1qEA+68x6CTMQIWAlD3Sl63fUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}