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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cac9c310d7eb5d0294669d69e72f46d4db2e1a0fe5546018e6ba2c42ab60c604' 
  AND token = 'MsCekgXhQmBXZIFGU7yAbjQq9ntapr8+L3uGSwFlw2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}