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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a4e80ba4b009b592226748b44bdb110e3a655c9689663323e50d6c5b23fdbb' 
  AND token = 'Z/fjindBwBmrOYXxV2WTZb2b9PhR9Aq2MxZ59AKj1CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}