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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4450587695a9534671f6ac6845b2b1706f1bf4d926cef0fd6e4a59b1b852ac81' 
  AND token = 'wLiE0LpWSyUrRYEnBPP+ETLDNIEaAay3hFkpoVoOkt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}