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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449c2a71875ed0d94190cef1f327f681d24f2059d5cef38757576f84ee6486b8' 
  AND token = 'odJ+E5J3L3Qm3NijpPejV7aAJFX5h3zMJ5lhUkWmXTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}