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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34191b7af2aa61b9801fae429e70af0b04fb19ec8ba8f02ab875cff3d60e5ce7' 
  AND token = 'I3a2FT0YvRFBi13wWoi+5bPDQLfcPIH5u0dVyaQ4/q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}