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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da2f18810c9cffefba266c0d5f05084cd7ad0c81fd1d8b02bb684958cc5a897d' 
  AND token = 'MIO7Emz6aqCcfXQEmv68QfVYfK1FFYg9LM9HadxLFKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}