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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd7bfe5c0b3bd942955fac7ac47f874d13321805445ac03c8335fb5bb375f0c' 
  AND token = '/Z5DVXQeWouAAaWPDxGfgQAuhPTdIQtjgH3Lan0wt0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}