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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ae9b452142c918627407a6537eb9cd46f40165a301d9cf7fff78ead8dde50f6' 
  AND token = 'rtycza9H0OY/Kc8A9WaweI4pINik+uRLj4UpR9vLjbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}