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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcfdf4933e1e0079f8bcba593418aefce31f8a83b583c0e936a220884036a912' 
  AND token = 'gii/aqAt8CWY6ZqAVJ1+doLKSU0FjDPoNmxBkCWfBnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}