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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b777280667dc6610e673c00abd3eb89e8dfe8027b7019b85e7fb67e73b840018' 
  AND token = 'hOgn98acaiDIiE992exwmMtkaC7rUAFh23mVWJJdMbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}