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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41079a9c8629382ab1e74c8d89eeb0160f11379dddf37997ed42a69af943206e' 
  AND token = 'NrdWMX5GKac0K4KF+B1glZgXMwyk50bI3YZl81kk2Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}