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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38926c30155878ae7e5b3b8ef6d47860bcb353d2fcf7f58772bcfa08854b238' 
  AND token = 'PvsARBv0oxsgpiTOC6GCf6CJ+xkwUbFczRL1JRqdrI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}