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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459f1e2968be760bfe8d821caa60232cb8f20eab49d95517dc47ef5470f20335' 
  AND token = 'NpLsZtE9Nt3K+hmaqPu1xSWMeMcAx4w5lbTt5KZeP74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}