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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295ad4edaaefb2acecb2e63c9dc42a55dfc0d27a135725218e98c04ad9a14b24' 
  AND token = 'DMugT8TlDcVZAYxBZRDOC2+EEuhwxTqWjy2VFKq2TVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}