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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63a65e7a4df7391b07df4bfe2b4d10f34ff591a257f859129929db49bd0c1260' 
  AND token = 'jZvDLrm2nINg2K3CnfeyfvZT3q+BAT6NbohzDl2Ir90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}