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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cb778f6a0b2ba69fa83e0a585ed555f0fc4e60ea6014e86303c3ef7c49e138' 
  AND token = '4LUwnIzLPPn1npzVFMyl06vHkFvSKVHWcY3tEFTDv5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}