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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a49f8ad36fe2565a6ea1da106e29a1ea54ba9d0a3d14fa9e91889b2bd67814f' 
  AND token = 'iVdWnd8z6ChXFZfBmHqSfbLSCKJrb/tlhGCXODa7UH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}