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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37403da44db2f1bbf62f90c797ac13f8a692f9cd087b485ebd9ffdf5a8293259' 
  AND token = 'QISkM5B8OEAePdttmursJGmleE0ltbYRgjbkwYHgJrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}