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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0663ac0a62d5090d9476abd2a68c76c5be73c147feff4ae72e8f93c22d901cbf' 
  AND token = '1PmGG19xHqVFHZRoa1kCE48NTEuWDKL2pLmDlj2H06s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}