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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac50b22cbb73e9888b827aa93ccad42d9f6b055372f7c5b481fbefafd1f763d' 
  AND token = 'Tdxx8jEss3s/3Vvz5vpfxDJjgfJT5CT/J/Ft4Xf0rhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}