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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac224d553627c060ba853d0e7a46c5179f28e03c3482eb1b48792315a653463' 
  AND token = '3jKQwc8z5sNN3ETzQTxiwoK26nLOt1A8icmjPCyWCEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}