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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab46f8343a9137cd7074daef55ca608a37d4e9d51462e1e9a4ad691055f74cf2' 
  AND token = 'S4Rn8rApMKFpy3COESZY7VvU4c3yWI83czVhw4/Vc30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}