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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41106e505bb456c1756d74e19d22b21ba4de31b49e22c25f4abaedf63f00ada5' 
  AND token = 'u0PXziAw+B0aGw3zBGyr989wFkvd12vU8DYwabfoudk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}