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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd0ed4f3e1dea67636f5bb34e4857b3235ad8ca4a2fd67058de321d006f210a3' 
  AND token = 'A0ZxIsCFRQZMrsZqq2dGL1pnqZ7SVoqDRiv6z8eU6vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}