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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea0fabd96bb154f99a4c8df8940a542967ed876dc2ba0da032fc1c1abd806b1' 
  AND token = 'ycFIPhK/HTXgvkwC3L2WBPUCkgFj7KmB/98c7WnCATs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}