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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de1da4c5d6e220876f87b282467abbb27063af178eaf4c4bdfc3f48388cc57a' 
  AND token = 'gAV1LiK+VJjkLrmt4P1HrBdiCqYMxMHa1c729M6dwUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}